Tired of sky-high drug prices and confusing insurance battles? Mark Cuban’s Cost Plus Drug Company is throwing a lifeline to patients drowning in medication costs. By cutting out the predatory middlemen and embracing radical transparency, Cost Plus Drugs is delivering life-saving medications at prices you won’t believe. This isn’t just about saving a few dollars; it’s about reclaiming your right to affordable healthcare.
Transparency: The Cure for Price Gouging
Cost Plus Drugs operates on a simple, revolutionary principle: transparency. They buy generic drugs directly from manufacturers and sell them to you with a straightforward 15% markup, plus a flat pharmacy fee and shipping. No hidden rebates, no secret deals, just honest pricing. This “cost-plus” model exposes the outrageous markups rampant in the traditional pharmaceutical system, where PBMs and insurers often inflate prices for their own profit.
Jaw-Dropping Price Differences: Real Medications, Real Savings
The proof is in the prices. Vaginal estrogen cream, crucial for many women’s health needs, costs a staggering $293.66 through Medicare Part D. Cost Plus Drugs? Just $22.48 for the same tube. For cancer patients battling leukemia, Imatinib, a vital chemotherapy drug, can list for $2500 per month at regular pharmacies. Cost Plus Drugs offers it for a mere $13.40. But the savings don’t stop there.

Consider these additional examples of price discrepancies, highlighting the potential savings with Cost Plus Drugs compared to typical insured prices:
| Medication | Condition | Typical Insured Price* | Cost Plus Drugs Price** | Potential Savings |
|---|---|---|---|---|
| Atorvastatin (20mg) | High Cholesterol | $25 – $50 | $5.60 | 76% – 93% |
| Amlodipine (10mg) | High Blood Pressure | $20 – $40 | $5.30 | 69% – 90% |
| Losartan (50mg) | High Blood Pressure | $15 – $30 | $6.40 | 58% – 79% |
| Metformin (500mg) | Type 2 Diabetes | $10 – $20 | $5.30 | 61% – 81% |
| Sildenafil (25mg) | Erectile Dysfunction/PAH | $40 – $80 | $7.29 | 95% – 97% |
* Typical Insured Prices are estimates and can vary widely based on insurance plan, pharmacy, and location.
** Cost Plus Drugs Prices include 15% markup, $5 pharmacy fee, and $5 shipping.
These are not isolated examples; across a wide range of generics, Cost Plus Drugs consistently offers prices drastically lower than insurance copays or traditional cash prices. Imagine the relief – medications you need, at prices that don’t break the bank.
A Lifeline for Everyone, Especially the Uninsured
Cost Plus Drugs isn’t just for those without insurance. Even with coverage, high deductibles, co-insurance, and formulary restrictions can leave you facing unaffordable medication costs. Cost Plus Drugs can be a game-changer for the uninsured, offering a direct path to affordable generics. But it also empowers the insured, providing a low-cost option when insurance falls short or simply costs more. No matter your insurance status, Cost Plus Drugs puts you back in control of your medication expenses.
Take Action Today: Don’t let inflated drug prices dictate your health. Discuss Mark Cuban’s Cost Plus Drug Company with your doctor or pharmacist. Ask if your prescriptions are available through Cost Plus Drugs. It’s time to demand transparency and affordability in healthcare – and Cost Plus Drugs is leading the charge.
References
- Dusetzina, S.B., et al. Patient-Level Savings on Generic Drugs Through the Mark Cuban Cost Plus Drug Company. JAMA Netw Open. 2024;7(6):e2416892. https://pmc.ncbi.nlm.nih.gov/articles/PMC11179122/
- Xu, R., Escott, M., & El Haraki, A. S. The Mark Cuban Cost Plus Drug Company Effect on Urogynecologic Drugs. Urogynecology (Phila). 2025 Jan 24. doi: 10.1097/SPV.0000000000001653. https://pubmed.ncbi.nlm.nih.gov/39868809/
- Cost Plus Drugs Website. https://costplusdrugs.com/ (Note: Used for general information about pricing model and drug availability, not directly cited in chart prices which are estimates based on search results and typical ranges.)
Disclaimer: Price comparisons are for illustrative purposes only and may vary. Always check current prices on Cost Plus Drugs website and with your insurance/pharmacy for the most accurate information. At the time of writing I am in no way affiliated or sponsored by Cost Plus Pharmacy and all information is for the purposes of education and advocacy.

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