Could Probiotics Be the Future of Acne Treatment?

Acne is a common skin condition that affects millions of people worldwide. It can have a significant impact on a person’s quality of life, both physically and emotionally. While there are many effective treatments available for acne, scientists are always looking for new and innovative ways to address this condition. One promising avenue of research is the use of probiotics.  

Probiotics are live microorganisms that are similar to the beneficial bacteria that live in our gut. They are often referred to as “friendly bacteria” or “good bacteria.” Probiotics can be found in a variety of foods, such as yogurt, sauerkraut, and kimchi. They can also be taken as supplements.

The Gut-Brain-Skin Connection

Over 70 years ago, dermatologists John H. Stokes and Donald M. Pillsbury first proposed a gastrointestinal mechanism for the overlap between depression, anxiety, and skin conditions such as acne. They hypothesized that emotional states might alter the normal intestinal microflora, increase intestinal permeability, and contribute to systemic inflammation.  

This is often referred to as the “gut-brain-skin axis.” The gut-brain-skin axis is a complex network of communication between the gut, the brain, and the skin. This network is thought to play a role in a variety of health conditions, including acne.

How Probiotics Might Help Acne

Probiotics are thought to help acne by improving gut health and reducing inflammation. A healthy gut microbiota can help to reduce intestinal permeability and systemic inflammation, which are both thought to contribute to acne.

There is growing evidence to suggest that probiotics may be a helpful addition to acne treatment. A study published in the journal Nutrition found that a probiotic drink containing Lactobacillus bacteria improved clinical aspects of acne over 12 weeks. The probiotic drink led to significant reductions in total lesion count and sebum production.  

Another prospective study compared the use of probiotics against isolated antibiotic therapy (Minocycline) and combination probiotic-antibiotic therapy. Notably ALL groups experience improvement in their acne, with the combination antibiotic-probiotic group demonstrating the greatest improvement. This highlights that probiotics may be effective both as an alternative or adjunct to traditional therapy.

What Are the Best Probiotics for Acne?

More research is needed to determine the best strains of probiotics for acne. However, some research suggests that Lactobacillus and Bifidobacterium strains may be helpful.

How to Take Probiotics for Acne

Probiotics can be taken in a variety of ways. They can be found in supplement form, or they can be consumed in foods such as yogurt, sauerkraut, and kimchi.

It is important to talk to your doctor before taking probiotics, especially if you are taking any other medications.

Future Considerations

More research is needed to determine the full potential of probiotics for acne. However, the available evidence suggests that probiotics may be a helpful addition to acne treatment.

In the future, scientists may be able to develop targeted probiotic therapies for acne. These therapies would use specific strains of probiotics that have been shown to be effective for acne.

Action Items

  • Talk to your doctor about whether probiotics are right for you.
  • If you decide to take probiotics, be sure to choose a reputable brand.
  • Follow the directions on the label carefully.
  • Be patient, as it may take several weeks or months to see results.
  • Consider incorporating probiotic-rich foods into your diet.
  • Remember that a healthy lifestyle, including a balanced diet and stress management, is also important for managing acne.

Additional Citations:

Bowe, W.P., Logan, A.C. Acne vulgaris, probiotics and the gut-brain-skin axis – back to the future?. Gut Pathog 3, 1 (2011). https://doi.org/10.1186/1757-4749-3-1

Sutema, I. A. M. P., Latarissa, I. R., Widowati, I. G. A. R., Sartika, C. R., Ciptasari, N. W. E., & Lestari, K. (2025). Efficacy of probiotic supplements and topical applications in the treatment of acne: A scoping review of current results. Journal of Experimental Pharmacology, 17, 1–14.

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